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A single nucleotide G to A substitution located 181 bp downstream of Zeb1 exon 1 and 12 bp downstream of exon 1 of the predicted gene Gm10125, a loxP site, and IRES-lacZ cassette, and a floxed inverted pgk-neo cassette were inserted via homologous recombination. Cre mediated recombination removed the IRES-lacZ and pgk-neo cassettes. This mutation is designed to duplicate the one found in Zeb1Tw mice (J:177274)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
