The following elements were placed downstream and in frame of exon 2: a loxP, EGFP, self-extracting and FRT-flanked neo cassette, and an additional loxP site. The presence of the Flp gene introduces a premature stop codon and produces a truncated protein. The absence of transcript expression was confirmed by in situ hydridization on brain sections. (J:176339)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count