The following elements were placed downstream and in frame of exon 2: a loxP, EGFP, self-extracting and FRT-flanked neo cassette, and an additional loxP site. The presence of the Flp gene introduces a premature stop codon and produces a truncated protein. The absence of transcript expression was confirmed by in situ hydridization on brain sections. (J:176339)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion, Intragenic deletion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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