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The transgene consists of the CAG promoter, a cassette containing a loxP-flanked mRFP1 gene and 4 tandem polyadneylation sites, the human SOX9 cDNA with a 3x hemagglutinin epitope tag, and an IRES-EGFP-polyA sequence. The vector was injected into C57BL/6 oocytes to generated mice. 8 founders were obtained and one line that showed significant levels of (ubiquitous) mRFP1 expression was chosen for further study. (J:176952)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
