An FRT site was inserted upstream of exon 7 and an floxed pgk-neo cassette and FRT site were inserted downstream of exon 7 via homologous recombination. Western blot analysis of homozygous adults indicated reduced but detectable levels of protein expression. (J:176889)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count