The transgene comprises a yeast artificial chromosome (YAC) from the CEPH Whole Genome MegaYAC Library carrying a 430-kb fragment of DNA from human Chromosome 21 that includes the potassium inwardly-rectifying channel, subfamily J, member 6 gene, KCNJ6 (also called GIRK2, KIR3.2 or HUM21ES123), which is expressed in the brain both in humans and in mice bearing the YAC as a transgene. No copy number or confirmation of full-length status is provided for this line. (J:128897)