The targeting vector contained a 13.1 kb fragment of Col10a1 and an IRES-cre-pA sequence/Frt-flanked PGK-neo bovine pA cassette. Homologous recombination in G4 ES cells resulted in insertion of the vector sequence into the 3' UTR of the endogenous Col10a1 locus. Chimeras were subsequently bred to C57BL/6 mice. (J:176952)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
1
1
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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