Cre-mediated recombination removed the EGFP and puro cassettes. The Pax8, IRES, and nuclear localized lacZ remain intact within intron 1. Expression of Pax3 is replaced with expression of Pax8. (J:176192)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count