A loxP site was inserted upstream of exon 1and an ApaLI site and floxed neo cassette was inserted 288 bp downstream of exon 2 via homologous recombination. (J:175535)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count