A loxP site and EcoRI siter were inserted 200 bp upstream of the transcription initiation site and a loxP site, EcoRI site, and FRT flanked neo cassette were inserted36 bp downstream of the stop codon via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exons 1 and 2. (J:175781)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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