A loxP site and EcoRI siter were inserted 200 bp upstream of the transcription initiation site and a loxP site, EcoRI site, and FRT flanked neo cassette were inserted36 bp downstream of the stop codon via homologous recombination. Flp mediated recombination removed the neo cassette. (J:175781)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count