A targeting vector was designed to insert a loxP site upstream of exon 5, and a frt-flanked neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 6. Flp-mediated recombination removed the neo cassette. (J:175748)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count