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The mouse promoter drives brain-specific expression of the human cDNA encoding the first 586 N-terminal amino acids (N586) and an expansion of the glutamine tract to 82 (82Q). The transgene was co-integrated with a transgene in which the human promoter drives skin-specific expression fo EGFP. Lines C62 and C63 were generated with the later expressing at higher levels than the former. (J:173756)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
