A loxP site was inserted 5' of exon 6 and an FRT flanked inverted neo cassette and second loxP site were inserted 3' of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:174679)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count