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A construct was produced with the CAG promoter separated from the 3.5 kb lacZ gene by a loxP-flanked STOP signal. The lacZ sequence was fused to a nuclear localization signal. The 8.0 kb linearized fragment was injected into BDF1 zygotes to created transgenic mice. 3 founders (#'s 1,2, and 3) were generated having 5, 10, and 15 copies of the transgene, respectively. (J:98285)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
