A loxP site was inserted upstream of an exon 11 and a floxed neo cassette and mutant version of exon 11 with an in frame deletion of the 49 RING domain encoding amino acids were inserted downstream of exon 11 via homologous recombination. (J:174368)
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A loxP site was inserted upstream of an exon 11 and a floxed neo cassette and mutant version of exon 11 with an in frame deletion of the 49 RING domain encoding amino acids were inserted downstream of exon 11 via homologous recombination. (J:174368)