Log In|Sign Up
EN
This transgene consists of the full-length human TATA box binding protein, TBP, with the 36 CAA/CAG repeat region expanded to 109 repeats under the control of the mouse Pcp2 promoter. A copy number of 10-20 is seen for line 69. Expression of the transgene occurs mainly in the cerebellum and brainstem, and at lower levels in cortex and hippocampus. (J:174239)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
