The transgene contains the cloned regulatory/immunosuppressive T cell line (designated 2H6) from the pancreatic lymph nodes of a diabetic NOD mouse that specifically recognizes the insulin B chain peptide 12-25 or 9-23 (2H6 regulatory TCRalpha (Valpha6 (Valpha6/Jalpha45/Calpha)) and TCRbeta (Vbeta14 (Vbeta14/Dbeta1.1Jbeta2.3Cbeta2))). (J:108964)