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A 3.7 kb fragment of the upstream region of the mouse Dct gene drives expression a lacZ gene. Four founders expressing the transgene were generated. All lines show a similar pattern of expression. Transgene expression is detected in early retinal pigment epithelium (RPE), early neural crest cells, optic nerve, and neural crest-derived neuronal cells. This transgene can be used to study melanocyte development. (J:134392)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
