A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and second loxP site were inserted in the untranslated region of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:173242)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count