The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 4875bp between positions 82624943-82629817 of Chromosome 6 (Build GRCm39). Sequencing of the first exon revealed that the deletion cassette is inserted 94 bp after the start of exon 1. Western blot analysis confirmed loss of protein expression in E13.5 homozygous mutant embryos. (J:136110, J:261973)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
Insertion, Intragenic deletion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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