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RMCE replaced the floxed luciferase gene in Gt(ROSA)26Sortm1Dwir with an inverted fusion protein of the hsp 73-capturing N-terminal viral J domain of SV40 T-Ag (cT77); 108-residue of the Ovalbumin fragment (aa 246-353 with a isoleucine to valine change at position 258) with well-characterized Kb- and Ad/b-binding epitopes (specifically recognized by OT-I or OT-II/D011 TCR), and the eGFP reporter. Cre-mediated recombination is required to achieve expression of the fusion protein. (J:173806)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
