A loxP site was inserted upstream of exon 1 and a loxP-flanked neomycin and thymidine kinase selection cassette was inserted downstream of exon 2. Cre-mediated recombination removed the neomycin cassette. (J:94077)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count