An FRT-flanked selection vector containing a neomycin resistance gene and a single 5' loxP site was inserted upstream of exon 2 of the Mgl2 gene and a second loxP site was inserted downstream of exon 10 of the Clec10a gene. The selection cassette was subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(ACTFLPe)9205Dym. (J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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