One loxP site was inserted in intron 3 just 5' to exon 4. A neomycin resistance cassette, a second loxP site and an EGFP construct were inserted 3' to exon 8. Cre mediated excision will remove exons 4-8 and the resistance cassette. This results in a fusion protein composed of exons 1-3 and EGFP. (J:173947)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion
--
1
3
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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