A cre-expression cassette, followed by a polyadenylation sequence, was inserted into BAC clone RP23-16C2 at the initiating ATG codon of the first coding exon of the Chrna7 gene so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. (J:100256)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count