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A targeting vector with the cre/ERT2 sequence, polyadenylation site, and an Frt-flanked neomycin cassette inserted into the ATG site of Msx1 in a plasmid was generated by homologous recombination in bacteria. The linearized targeting vector was electroporated into ES cells and targeted clones were used to generated chimeras. F1 offspring were crossed to Flp deleter mice to delete the neo marker. (J:173525, J:194129)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
