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The mouse bacterial artificial chromosome (BAC) RP23-392P11 containing the Slc32a1, solute carrier family 32 (GABA vesicular transporter), member 1, gene, was modified by insertion of sequence encoding iCreER at the Slc32a1 translation initiation ATG, and addition of a Kozak sequence upstream of the ATG. This BAC also contains these additional genes Adig (adipogenin), Arhgap40 (Rho GTPase activating protein 40), AK134637, BC072662, and Actr5 (P5 actin-related protein 5 homolog (yeast)). The modified BAC was used to generate the VGAT-iCreER transgene, which was microinjected into C57BL/6NTac fertilized eggs. Founder line 3 was subsequently established. (J:173675)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
