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Cre-mediated recombination of Trp53tm1.1Awbr removed exons 3 and 4, which encode the first 122 amino acids (transactivation and proline rich domains). The predicted protein corresponds to human isoform delta133p53 generated from an alternative transript initiation site in intron 4. (J:173271)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
