A targeting vector was designed to insert an internal ribosomal entry site, nuclear-localized Cre recombinase gene, and polyA signal (IRES-Cre-pA) followed by an FRT-flanked PGK-Neo cassette into the 3' untranslated region of the cut-like homeobox 2 (Cux2) locus. Flp-mediated recombination removed the FRT-flanked PGK-Neo cassette. (J:151755)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count