The transgenic construct consists of a sequence fragment encoding a consensus Kozak signal, a nuclear localization signal and cre recombinase inserted at the start codon of the mouse Nppa genomic sequence (-3 to +4 kb relative to the transcription start site). The 0.7 kb proximal regulatory region, containing the promoter and silencer and enhancer sequences, is included, as is the NRSE (neuron-restrictive silencer element) in the 3' UTR. (J:86158)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
--
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8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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