The transgene contains a human UBB promoter driving ubiquitous expression of a floxed DsRED*T3/stop cassette, emerald GFP (EmGFP) usptream of two different short hairpins targeting Sarm1, two polyadenylation sequences, and tandem cHS sequences. Cre-mediated recombination removed the DsRED*T3/stop cassette. Three lines were generated with lines 1 and 3 exhibiting higher EmGFP expression compared with line 2. The pound symbol is used when no line is specified and/or lines are pooled. (J:172355)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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