An FRT flanked pgk-neo cassette and loxP sit were inserted into intron 4 and a loxP site was inserted into intron 7 via homologous recombination. Flp mediated recombination removed the pgk-neo cassette leaving exons 5-7 floxed. (J:172442)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count