A targeting vector containing a PGK-neo cassette was used to insert loxP sites flanking exon 41 and the selection cassette. Cre-mediated recombination removed exon 41 and the FRT-flanked neo cassette. (J:172418, J:188435)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count