Exon 9 was replaced with a floxed exon 9, which contained nucleotide substitutions that result in the amino acid substitution of leucine for valine at position 280 (V280L) and valine for cysteine at position 298 (C298V), and an FRT-flanked neo cassette. Cre mediated recombination removed exon 9. (J:164548)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Insertion, Intragenic deletion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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