The Tmub1 gene consists of 3 exons. Coding exons 1 and 2 were targeted (NCBI accession NM_022418.1) by homologous recombination and replaced with a LacZ/neomycin selection cassette. Disruption of the target gene was confirmed by Southern hybridization analysis and multiplex PCR. (J:161786, J:171883)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count