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The Prap1 gene consists of 5 exons. Coding exons 1 through 5 were targeted (NCBI accession NM_009475.1) by homologous recombination. Disruption of the target gene was confirmed by Southern hybridization analysis. Western blot analysis using novel PRAP1 rabbit antisera demonstrated the absence of protein expression in small intestine and uterine whole tissue from homozygous mutant mice. Immunofluorescence staining confirmed the absence of detectable signal in duodenal tissue. (J:171883, J:304152)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
