The Adam18 gene consists of 20 exons, with the start codon located in exon 1 (NCBI accession NM_010084.1). Exons 1 and 2 were targeted by homologous recombination. Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count