Germ-line cre deletion of the loxP-flanked EGFP cassette generated this Flp only-responsive reporter allele. In presence of Flp (or Flpe), the Frt-flanked PGK-Neo stop cassette is excised allowing expression of lacZ in Flp-expression progenitor cells.
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count