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This transgene contains the cre recombinase coding sequence and the metallothionein 1 polyadenylation signal between the Wnt1 basic promoter and intron, which is followed by the inverted rhombomere 4 (r4) enhancer and the r3/r5 repressor from the Hoxb1 locus. These elements together restrict expression to rhombomere 4 in the hindbrain of the developing embryo. (J:20433, J:197162)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
