A transgene containing the human promoter and gene with its liver control region that drives liver-specific expression of an optimized reverse tetracycline-controlled transactivator (rtTA*M2) in place of exon 3 and a transgene containing the tetracycline responsive element that drives inducible expression of the mouse cDNA with 3 C-terminal myc tags were co-injected. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:172091)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count