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A cDNA encoding exons 1-383 and an engineered stop codon at position 384 and a floxed neomycin selection cassette replaced the endogenous coding sequence. The resulting allele lacks the sequence encoding amino acids 384-527 of the intact protein. The selection cassette was subsequently removed by cre excision. (J:171970)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
