A construct consisting of a splice acceptor site, a floxed transcriptional stop cassette and a mutant mouse Pik3ca cDNA, encoding for a histidine 1047 arginine substitution, was inserted into intron 1 via homologous recombination. (J:170898)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count