The env gene from the LAV strtain of HIV-1 was truncated to encode gp120 amino acids 1-509 and inserted in exon 1 of a modified murine Gfap gene. Five lines (2, 3,10, 16, 37) were established which varied in level of expression. Level of expression did not correlate with transgene copy number. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:146427)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6 x SJL
--
Insertion
--
--
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14

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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