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A transgene, which contained the nasopharyngeal carcinoma-derived human gene with upstream promoter, coding sequence, and 3' untranslated region, inserted into intron 1 and resulted in a 7.2 kb deletion from intron 1. Western blot analysis confirmed that the transgene failed to express in skin extracts. The absence of endogenous transcript expression was confirmed by RT-PCR on skin, brain, heart, lung, liver, stomach, intestine, and kidney extracts. (J:171677)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
