A UPA gene trap vector inserted into the sixth intron of the gene. This mutation is predicted result in the production of a truncated transcript. Immunofluorescence experiments of the small intestine and kidney proximal tubule of 3-day-old homozygous mutant pups showed that no expression is detected in the small intestine and kidney proximal tubule compared to control littermates. (J:237439)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Gene trapped
Insertion of gene trap vector
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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