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EN
The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 8162bp between positions 49536744-49544905 of Chromosome 4 (Build GRCm39). The cassette replaced 3' of exon 2 through 5' of exon 9. Enzyme activity assays of liver lysates revealed that activity toward fructose 1-phosphate was undetectable, and resulted in a change in the fructose 1,6-bisphosphate:fructose 1-phosphate activity ratio from 1.7 in wild-type mice to over 10 in homozygous mutant mice, indicating that any remaining aldolase activity was due to aldolase A. (J:136110, J:220330)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
