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A loxP site was inserted upstream of exon 13b and a floxed ura/neomycin selection cassette was placed downstream of exon 14b. Cre expression results in removal of 2.5kb of sequence including both exons 13b and 14b. The deleted locus can no longer express the TrkC.T1 isoform. Full length product is expressed at a level of 1.6X normal however. (J:171397)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
