A loxP site was inserted upstream of exon 1 and an FRT-loxP-neo-FRT-loxP cassette was introduced downstream of exon 1 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:171226)
Basic Information
(C57BL/6J x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count