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Mice carrying Tg(Hba1-Gfp)1Ew were treated with ENU. ENU induced a T to A transition in exon 2 that changes an isoleucine to asparagine in the highly conserved Forkhead domain. Northern and western blot analysis indicate this mutation does not greatly affect mRNA or protein expression. (J:99816, J:170710)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
