An FRT- and loxP flanked neo cassette was inserted upstream of exon 3. A loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette, leaving exons 3 through 5 floxed. (J:170941)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count